Severe Relapsing Clozapine-Withdrawal Catatonia

Clozapine withdrawal catatonia or lethal catatonia in a schizoaffective patient with a family history of Parkinson's disease.

Catatonia Secondary to Sudden Clozapine Withdrawal: A Case with Three Repeated Episodes and a Literature Review

A literature search identified 9 previously published cases that were considered as possible cases of catatonia secondary to sudden clozapine withdrawal. Two of these 9 cases did not provide enough information to make a diagnosis of catatonia according to the Diagnostic and Statistical Manual, 5th Edition (DSM-5). The Liverpool Adverse Drug Reaction (ADR) Causality Scale was modified to assess ...

Takotsubo Cardiomyopathy and Catatonia in the Setting of Benzodiazepine Withdrawal

We report two serious and unusual complications of benzodiazepine withdrawal in a single patient: takotsubo cardiomyopathy and catatonia. This 61-year-old female patient was brought to the emergency department with lethargy and within hours had declined into a state of catatonia. Although there was never a complaint of chest pain, ECG showed deep anterior T-wave inversions and cardiac enzymes w...

Severe Withdrawal (and Recovery)

Abstract. The problem of how to remove information from an agent’s stock of beliefs is of paramount concern in the belief change literature. An inquiring agent may remove beliefs for a variety of reasons: a belief may be called into doubt or the agent may simply wish to entertain other possiblities. In the prominent AGM framework [1, 8] for belief change, upon which the work here is based, one ...

The Treatment of Clozapine-Withdrawal Delirium with Electroconvulsive Therapy

Clozapine, a commonly used atypical antipsychotic, can precipitate a severe withdrawal syndrome. In this report, we describe a case of delirium with catatonic features emerging after the immediate cessation of clozapine subsequent to concerns of developing neuroleptic malignant syndrome. After multiple treatments were found to be inefficacious, electroconvulsive therapy (ECT) was initiated, res...